Six Figure Work

Forward Deployed Engineer (FDE), Life Sciences - NYC

OpenAI

Company websiteopenai.com (OpenAI, opens in new tab)

Base salary $185K  to $300K

Employer-published annual base salary, USD. Advertised base range in New York City, NY

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  • LocationNew York City, NY
  • WorkplaceHybrid
  • Status at last checkSource accepting applications when checked
  • Last checked (1 h ago) · observed since

About this job

About the Team

OpenAI’s Forward Deployed Engineering team partners with global pharma and biotech, CROs, and research institutions to deploy existing expertise across the R&D value chain to help customers design and ship production-grade AI systems. We operate at the intersection of customer delivery and core platform development, converting early deployments into repeatable system standards and evaluation practices that scale across regulated environments.

About the Role

We are hiring a Forward Deployed Engineer (FDE) to push the frontier on what is possible today across drug discovery (e.g., target identification, molecular design, pre-clinical) and development (e.g., trial design, trial ops, biostats) by leading end-to-end deployments of our models inside life sciences organizations and research institutions. You will work with customers who are deep experts in their scientific or operational domains, translating real-world data, infrastructure, and constraints into production systems.

You will measure success through production adoption, measurable workflow impact, and eval-driven feedback loops, including evaluation benchmarks and acceptance criteria, that inform product and model roadmaps. You’ll work closely with our Product, Research, Partnerships, GRC, Security, and GTM to deliver in regulated contexts, including inspection readiness with audit trails and traceable evidence.

This role is based in New York. We use a hybrid work model of 3 days in the office per week. We offer relocation assistance. Travel up to 50% is required.

In this role, you will:

  • Design and ship production systems around models, owning integrations, data provenance, reliability, and on-call readiness across research, clinical, and operational workflows.

  • Lead discovery and scoping from pre-sales through post-sales, translating ambiguous workflow needs into hypothesis-driven problem framing, system requirements, and an execution plan with measurable endpoints.

  • Define and enforce launch criteria for regulated contexts, including validation evidence, audit readiness, outcome metrics, and drive delivery until we demonstrate sustained production impact.

  • Build in sensitive scientific data environments where auditability, validation, and access controls shape architecture, operating procedures, and failure handling.

  • Run evaluation loops that measure model and system quality against workflow-specific scientific benchmarks and use results to drive model and product changes.

  • Distill deployment learnings into hardened primitives, reference architectures, validation templates, and benchmark harnesses that scale across regulated life sciences environments.

You might thrive in this role if you:

  • Bring 5+ years of software/ML engineering or technical deployment experience with customer-facing ownership in biotech, pharma, clinical research, or scientific software; PhD, MS, or equivalent applied experience in a life sciences relevant field encouraged.

  • Have owned customer GenAI deployments end-to-end from scoping through production adoption, and improved them through evaluation design, error analysis, and iterative evidence generation that tightens acceptance criteria over time.

  • Have delivered AI systems in trial design, regulatory writing, or scientific operations where validation strategy, auditability, compliance constraints, and reviewer expectations shaped system design and rollout.

  • Communicate clearly across scientific, clinical, model research, technical, and executive audiences, translating technical tradeoffs into decision quality, risk posture, and measurable outcomes with credibility.

  • Apply systems thinking with high execution standards, consistently turning failures, escalations, and audit findings into improved operating standards, validation artifacts, and repeatable deployment playbooks.

About OpenAI

OpenAI is an AI research and deployment company dedicated to ensuring that general-purpose artificial intelligence benefits all of humanity. We push the boundaries of the capabilities of AI systems and seek to safely deploy them to the world through our products. AI is an extremely powerful tool that must be created with safety and human needs at its core, and to achieve our mission, we must encompass and value the many different perspectives, voices, and experiences that form the full spectrum of humanity. 

We are an equal opportunity employer, and we do not discriminate on the basis of race, religion, color, national origin, sex, sexual orientation, age, veteran status, disability, genetic information, or other applicable legally protected characteristic.

For additional information, please see OpenAI’s Affirmative Action and Equal Employment Opportunity Policy Statement.

Background checks for applicants will be administered in accordance with applicable law, and qualified applicants with arrest or conviction records will be considered for employment consistent with those laws, including the San Francisco Fair Chance Ordinance, the Los Angeles County Fair Chance Ordinance for Employers, and the California Fair Chance Act, for US-based candidates. For unincorporated Los Angeles County workers: we reasonably believe that criminal history may have a direct, adverse and negative relationship with the following job duties, potentially resulting in the withdrawal of a conditional offer of employment: protect computer hardware entrusted to you from theft, loss or damage; return all computer hardware in your possession (including the data contained therein) upon termination of employment or end of assignment; and maintain the confidentiality of proprietary, confidential, and non-public information. In addition, job duties require access to secure and protected information technology systems and related data security obligations.

To notify OpenAI that you believe this job posting is non-compliant, please submit a report through this form. No response will be provided to inquiries unrelated to job posting compliance.

We are committed to providing reasonable accommodations to applicants with disabilities, and requests can be made via this link.

OpenAI Global Applicant Privacy Policy

At OpenAI, we believe artificial intelligence has the potential to help people solve immense global challenges, and we want the upside of AI to be widely shared. Join us in shaping the future of technology.

Source: OpenAI on Ashby · View original posting (opens in new tab)

Pay in context

This role's base floor ($185,000) is above 61% of the 462 Data & ML roles in New York listed on this site; 9 others list the same floor. Their median floor is $175,300; the middle half runs from $150,000 to $200,000.

Only jobs on this site count, and each one publishes a base salary of $100,000 or more, so this compares six-figure jobs with each other, not with the whole market. Computed Nov 7, 2026.

This range next to 6 other live OpenAI roles with the nearest advertised base floor
Chart as a table
This range next to 6 other live OpenAI roles with the nearest advertised base floor
RolePublished base
Forward Deployed Engineer (FDE), Life Sciences - NYC (this listing)$185K - $300K
Product Evals Engineer, ChatGPT Learning$185K - $490K
Infrastructure Communications Lead$185K - $300K
Forward Deployed Engineer (FDE), Healthcare - Seattle$185K - $300K
Sourcing Manager, Core Products$185K - $205K
Forward Deployed Engineer (FDE) - NYC$185K - $300K
Forward Deployed Engineer (FDE) - Seattle$185K - $300K

Same $100K to $400K scale as every card. All OpenAI roles · How to read the bar

Observed changes

  1. Began meeting the published-salary criteria
  2. First observed on the employer's board
Observed since
Employer-stated posting date
2026-11-06
Where this pay comes from

Location as the employer wrote it: New York City

USD 185,000 – 300,000 · 1 YEAR · Salary

Method
Structured pay field published by the employer
Checked
Rule set
us-base-v2

The employer's job board publishes this pay as a dedicated data field. We read the field directly; no interpretation was needed.

What we verified

  • The pay figures come from the employer's own listing, quoted exactly above.
  • The pay is an annual base salary in US dollars with a minimum of at least $100,000.
  • The role was publicly listed on the employer's job board when last checked.

We do not verify what the employer will actually offer, whether the employer is still recruiting for the role, or anything beyond what the employer published. Full methodology.