Lead Software Engineer
Company websiteonoshealth.com (Onos Health, opens in new tab)
Base salary $200K to $275K
Employer-published annual base salary, USD. Advertised base range in San Francisco, CA
You apply on the employer's own site. Six Figure Work does not handle applications.
- LocationSan Francisco, CA
- WorkplaceHybrid
- Status at last checkSource accepting applications when checked
- Last checked (1 h ago) · observed since
About this job
About Onos Health
Onos Health’s mission is simple but ambitious: ensure every healthcare dollar goes toward delivering the highest quality care. Today, 30% of total U.S. healthcare spending is wasted due to ineffective care and administrative burden caused by misalignment between providers and payers.
Onos is addressing this by building the largest AI-driven healthcare data platform. Our models enables payers to make faster, more accurate decisions across their populations. By guiding members to the right care, Onos is channeling more dollars to high-quality care that drives better outcomes while making healthcare more affordable.
Onos is well-funded by some of the best healthcare investors and is working with the nation’s largest health plans. Come join a category-defining company and help reimagine healthcare for the better.
Why Onos?
Meaningful impact: Help fix what is fundamentally broken in healthcare
Direct collaboration: Work alongside experienced founders with deep healthcare and data expertise
Culture: Join a high-performing, transparent, and results-oriented team
Ownership: Significant responsibility and autonomy from day one
Opportunity: Play a pivotal role in building a fast-growing, category-defining healthcare AI company
The Role
We're seeking an experienced and highly capable engineering leader who is motivated to meaningfully improve the way healthcare is administered in the United States. You'll take ownership of developing a significant part of the Onos platform through hands-on development and technical leadership. As an early team member, you'll work closely with our founding team while helping to build and lead a growing engineering team. This role is a hybrid role based in San Francisco, where you'll be expected to work at our office in person 3 times a week.
What you'll be doing at Onos:
Architect workflows that utilize AI/ML to process claims, medical records and other data types to evaluate the optimal care path for health plan members
Lead the integration and rollout of the Onos platform for new enterprise customers to provide actionable insights and recommendations to health plan administrators
Own end-to-end development of new features and functionality for the Onos platform, including requirements gathering, scoping, architecting, implementation and testing to deliver timely and high quality outcomes
Establish engineering best practices and technical foundations for future team growth
Shape our technical roadmap, make key architectural decisions, and influence the company's product and technical strategy
Technical Challenges At Onos:
Develop an intelligent engine that ingests complex medical standards of care documents and evaluates provider adherence to guidelines
Design and implement robust and extensible systems to easily support many different kinds of enterprise workflows and integrations
Build AI/ML pipelines to analyze handwritten clinical notes, accurately extract important medical information, and automate recommendations for clinical reviewers
Scale our systems to process millions of healthcare records while maintaining strict security and compliance requirements
Tech Stack:
At Onos, we work with a modern tech stack where we continuously evaluate and adopt cutting-edge technologies as we scale.
Infrastructure/Systems: AWS (ECS, Bedrock, Glue, etc.), Docker, Github Actions, Terraform
Languages/Frameworks
Backend: Python, Django, Celery / Celery Beat, django-ninja, django-tenants
Frontend: NextJS, Typescript, Tanstack Query, Shadcn UI, Zod, Nuqs
Database/Storage: PostgreSQL (AWS RDS), S3, Clickhouse
Development Tools: Github, Jira, Claude Code, CoderabbitAI, Tusk
What we're looking for:
5+ years experience building software applications
Prior experience leading engineering teams as a tech lead or engineering manager
Strong product sense and system design skills with a track record of defining clear requirements, test scenarios, and acceptance criteria for complex systems
Customer obsessed and motivated to make an impact in the healthcare space
A hands-on technical leader who can architect robust and extensible systems, establish best practices with AI coding tools, and ship high quality production code
Bonus points if you have:
Worked with machine learning and large language models for end-user applications
Hands-on experience navigating healthcare data formats such as EDI X12, HL7, FHIR, and custom payer flat files
Benefits and Perks
Hybrid arrangement: 3 days/week at San Francisco office (Financial District)
Unlimited vacation policy
Paid parental leave
Medical, dental, and vision insurance
Pre-tax commuter benefits
401(k)
Significant equity as an early employee
Direct mentorship from experienced founders
Ground-floor opportunity to help build a team and culture
Regular team events and offsites
Company-provided equipment and home office setup
We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
Source: Onos Health on Ashby · View original posting (opens in new tab)
Pay in context
This role's base floor ($200,000) is above 70% of the 4,210 Software Engineering roles in California listed on this site; 151 others list the same floor. Their median floor is $176,500; the middle half runs from $149,241 to $204,000.
Only jobs on this site count, and each one publishes a base salary of $100,000 or more, so this compares six-figure jobs with each other, not with the whole market. Computed Nov 6, 2026.
This listingLead Software Engineer$200K to $275K
Lead Infrastructure Engineer$200K to $275K
Staff Software Engineer (AI)$200K to $275K
Senior Product Engineer$200K to $250K
Lead Data Scientist$200K to $225K
Forward-Deployed Product Manager$180K to $220K
Senior Data Analyst$170K to $200K
Chart as a table
| Role | Published base |
|---|---|
| Lead Software Engineer (this listing) | $200K - $275K |
| Lead Infrastructure Engineer | $200K - $275K |
| Staff Software Engineer (AI) | $200K - $275K |
| Senior Product Engineer | $200K - $250K |
| Lead Data Scientist | $200K - $225K |
| Forward-Deployed Product Manager | $180K - $220K |
| Senior Data Analyst | $170K - $200K |
Observed changes
- Began meeting the published-salary criteria
- First observed on the employer's board
- Observed since
- Employer-stated posting date
- 2025-12-17
Where this pay comes from
Location as the employer wrote it: San Francisco
USD 200,000 – 275,000 · 1 YEAR · Salary
- Method
- Structured pay field published by the employer
- Checked
- Rule set
- us-base-v2
The employer's job board publishes this pay as a dedicated data field. We read the field directly; no interpretation was needed.
What we verified
- The pay figures come from the employer's own listing, quoted exactly above.
- The pay is an annual base salary in US dollars with a minimum of at least $100,000.
- The role was publicly listed on the employer's job board when last checked.
We do not verify what the employer will actually offer, whether the employer is still recruiting for the role, or anything beyond what the employer published. Full methodology.
