Principal Software Engineer
Company websiteastera.org (Astera, opens in new tab)
Base salary $300K to $600K
Employer-published annual base salary, USD. Advertised base range in United States
You apply on the employer's own site. Six Figure Work does not handle applications.
- LocationUnited States
- WorkplaceOn-site
- Status at last checkSource accepting applications when checked
- Last checked (1 h ago) · observed since
About this job
About Astera
Astera is a private foundation on a mission to steer science and technology toward a better future. We believe the coming years will bring an era of unprecedented scientific and technological advancement as exponential progress in AI converges with central advances in other fields to accelerate innovation. This inflection point provides an unparalleled opportunity to fundamentally rethink the institutions, systems, and tools that drive progress. We have committed a $3.5B endowment to that work and fit the form of our support to the function it serves: grants, investments, and in-house research programs. We accept meaningful risk in the research we back and expect some of it to fail because transformative ideas are rarely the ones already proven. Our projects, and the foundation itself, operate like high-velocity startups, with a high performance bar and competitive compensation to match. We are searching for leaders who are compelled by the challenge of driving high-impact change in the way science is funded, conducted, and communicated. You can read more about our mission, vision, and programming at astera.org/vision.
Position Summary
We are looking for an ambitious Staff Software Engineer to help us reverse-engineer the human brain.
This role spans a broad spectrum of activities:
Define and architect high-performance infrastructure for training large-scale models and running complex simulations.
Design and optimize custom RL environments informed by neuroscience.
Set the organizational standard for clean, fast, production-grade code that boosts our research velocity.
Turn research prototypes into scalable production systems.
Identify and resolve the most critical and ambiguous technical bottlenecks, from low-level optimization to high-level strategy, to unblock the research team.
Qualifications
High-Velocity Craftsmanship: You set the bar for clean, maintainable, and well-tested code at a startup pace. You know how to balance engineering rigor with the need to iterate quickly on research prototypes.
System Architecture Intuition: You have proven success architecting complex systems from scratch. You understand multi-year trade-offs, and you can design infrastructure that survives the chaos of research.
Extreme Adaptability: You might be an expert in distributed systems today, but you are ready to become a novice in neuroscience tomorrow. You have a track record of diving into complex domains, mastering them quickly, and guiding others through them.
Mastery of Hard Problems: You have a track record of leading the resolution of difficult engineering challenges, whether it is massive scale distributed systems or kernel-level optimization. You do not shy away from what your peers consider hardcore.
Location & Visa
This role is in-person in Emeryville, CA.
Visa sponsorship may be available for qualified candidates.
Source: Astera on Ashby · View original posting (opens in new tab)
Pay in context
This role's base floor ($300,000) is above 97% of the 4,198 Software Engineering roles in California listed on this site; 5 others list the same floor. Their median floor is $176,500; the middle half runs from $149,200 to $204,000.
Only jobs on this site count, and each one publishes a base salary of $100,000 or more, so this compares six-figure jobs with each other, not with the whole market. Computed Nov 6, 2026.
This listingPrincipal Software Engineer$300K to $600K
Principal Software Engineer, Neuroscience Platforms$300K to $450K
Senior Roboticist$250K to $500K
Principal Hardware Engineer, Precision Instrumentation$250K to $400K
Principal AI Scientist (Polytope Bio)$250K to $350K
Senior Scientist, Structural Data Representation$220K to $260K
Head of Bio AI - Radial$400K to $600K
Chart as a table
| Role | Published base |
|---|---|
| Principal Software Engineer (this listing) | $300K - $600K |
| Principal Software Engineer, Neuroscience Platforms | $300K - $450K |
| Senior Roboticist | $250K - $500K |
| Principal Hardware Engineer, Precision Instrumentation | $250K - $400K |
| Principal AI Scientist (Polytope Bio) | $250K - $350K |
| Senior Scientist, Structural Data Representation | $220K - $260K |
| Head of Bio AI - Radial | $400K - $600K |
Observed changes
- First observed on the employer's board
- Began meeting the published-salary criteria
- Observed since
- Employer-stated posting date
- 2026-01-28
Where this pay comes from
Location as the employer wrote it: Emeryville HQ
USD 300,000 – 600,000 · 1 YEAR · Salary
- Method
- Structured pay field published by the employer
- Checked
- Rule set
- us-base-v2
The employer's job board publishes this pay as a dedicated data field. We read the field directly; no interpretation was needed.
What we verified
- The pay figures come from the employer's own listing, quoted exactly above.
- The pay is an annual base salary in US dollars with a minimum of at least $100,000.
- The role was publicly listed on the employer's job board when last checked.
We do not verify what the employer will actually offer, whether the employer is still recruiting for the role, or anything beyond what the employer published. Full methodology.
