Senior Director, Portfolio Strategy, Analytics & Enablement, Cardiometabolic Research
Company websitelilly.com (Eli Lilly and Company, opens in new tab)
Base salary $160,500 to $235,400
Employer-published annual base salary, USD. Advertised base range in Indianapolis, IN
You apply on the employer's own site. Six Figure Work does not handle applications.
- LocationIndianapolis, IN
- WorkplaceWorkplace not stated
- Status at last checkSource accepting applications when checked
- Last checked (1 h ago) · observed since
About this job
At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work—but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us.
The Portfolio Strategy, Analytics, & Enablement Lead for Cardiometabolic Research (CMR) will play a critical role in shaping & implementing CMR’s long-term vision, and will drive high-impact initiatives that foster growth, innovation, and operational excellence. As a strategic leader with vision, this individual will develop and implement initiatives that align therapeutic areas & cross-functional teams, ensuring seamless execution of organizational priorities while anticipating and responding to industry trends. Partnering closely with the CMR Lead Team (LT), they will own the portfolio fact base, regularly assess portfolio health, frame and run priority strategic projects, and support initiatives to improve communications, culture, and capabilities across CMR. This individual will also support efforts to communicate CMR portfolio status and progress across the broader organization, including to senior leadership.
Key Responsibilities
Portfolio strategy
- Lead portfolio-level strategy projects for CMR from the initial framing of the question through analysis, synthesis, and a recommendation to the Core Leadership Team. This includes assembling the working team, driving discussions, and delivering actionable outputs.
- Develop & maintain an integrated view of the CMR portfolio across therapeutic pillars, covering development stage, therapeutic modality, target novelty, risk-reward profile, and resource load. Use this view to evaluate portfolio health & make recommendations on improvements. This assessment will characterize the portfolio’s risk / reward distribution and project its expected shape as new pillars mature.
- Partner with therapeutic area leaders to keep program strategies and learning plans current, and surface cross-portfolio issues such as shared scientific risks, resourcing conflicts, and unexplored white space.
- Support the long-range planning cycle by translating CMR strategic priorities into plans, metrics, and dashboards that the Core Leadership Team can manage against through the year.
- Own the metrics and dashboards that track progress against CMR strategic objectives and establish them as the shared reference point in leadership discussions.
- Track the external landscape relevant to cardiometabolic research, including competitive, scientific, and regulatory developments, and bring the implications into portfolio and planning discussions.
Organizational enablement
- Support CMR's organizational communications, including monthly CMR updates to senior leadership, and development of content & execution of CMR-wide town halls in conjunction with therapeutic area leads.
- Drive program management and change management for CMR-wide capability initiatives. One example is the Strategic Thinking program, which trains scientists to clarify program strategy, identify and prioritize key issues, and design experiments that resolve them.
- Manage recurring organizational processes and campaigns, including the President's Award proposal process.
Basic Requirements
- Bachelor's degree in a life science, quantitative, or business field
- 6+ years of experience in pharmaceutical or biotechnology R&D with roles involving portfolio strategy, portfolio management, decision analytics, or strategy consulting serving those functions.
- Experience leading cross-functional strategy projects from framing through to a leadership decision.
Additional Skills and Preferences
- An advanced degree (PhD, PharmD, MS, or MBA)
- Working knowledge of drug discovery and early development in cardiometabolic disease (diabetes, obesity, cardiovascular disease, and their complications)
- Hands-on experience with portfolio analytics, including risk-adjusted valuation, probability of technical success, and resource and scenario modeling. The strongest candidates will be comfortable partnering with scientists on the quantitative work while owning the strategic framing themselves.
- A track record of designing metrics and dashboards that senior leaders rely on
- The ability to draw out diverse opinions in a matrixed organization and synthesize them into a recommendation that leadership will act on
- Clear written and spoken communication to scientific and non-scientific audiences, including governance committees
- A self-motivated individual who combines scientific curiosity with an enterprise mentality and a strong grasp of business concepts
Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.
Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women’s Initiative for Leading at Lilly (WILL).
Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is
$160,500 - $235,400Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.
#WeAreLilly
Source: Eli Lilly and Company on Workday · View original posting (opens in new tab)
Pay in context
This role's base floor ($160,500) is above 75% of the 4,121 Business Operations roles nationwide listed on this site; 6 others list the same floor. Their median floor is $135,000; the middle half runs from $117,000 to $160,434.
Only jobs on this site count, and each one publishes a base salary of $100,000 or more, so this compares six-figure jobs with each other, not with the whole market. Computed Nov 8, 2026.
This listingSenior Director, Portfolio Strategy, Analytics & Enablement, Cardiometabolic Research$160,500 to $235,400
Senior Director, Drug Safety Operations (remote)$160,500 to $259,600
Functional Service Team Executive/Senior Director, Clinical Delivery Capabilities – Exploratory Medicine Pharmacology (EMP)$160,500 to $235,400
Sr Director - Enterprise Connectivity & Network Services$159,000 to $233,200
Advisor - Lab Automation Software Engineer$157,500 to $253,000
Advisor - Lab Automation Software Engineer, AI-Integration$157,500 to $231,000
Director/Sr. Director - Medicinal Chemistry (synthetic macrocycles)$163,500 to $239,800
Chart as a table
| Role | Published base |
|---|---|
| Senior Director, Portfolio Strategy, Analytics & Enablement, Cardiometabolic Research (this listing) | $160,500 - $235,400 |
| Senior Director, Drug Safety Operations (remote) | $160,500 - $259,600 |
| Functional Service Team Executive/Senior Director, Clinical Delivery Capabilities – Exploratory Medicine Pharmacology (EMP) | $160,500 - $235,400 |
| Sr Director - Enterprise Connectivity & Network Services | $159,000 - $233,200 |
| Advisor - Lab Automation Software Engineer | $157,500 - $253,000 |
| Advisor - Lab Automation Software Engineer, AI-Integration | $157,500 - $231,000 |
| Director/Sr. Director - Medicinal Chemistry (synthetic macrocycles) | $163,500 - $239,800 |
Observed changes
- First observed on the employer's board
- Began meeting the published-salary criteria
- Observed since
- Employer-stated posting date
- 2026-11-05
Where this pay comes from
Location as the employer wrote it: US, Indianapolis IN • US, Remote
$160,500 - $235,400
- Method
- Employer text, read with fixed rules and re-verified
- Checked
- Rule set
- us-base-v2
The pay passage appears in the employer's own job text. Fixed, deterministic rules located it, and the passage below was checked against the stored copy of the posting.
What we verified
- The pay figures come from the employer's own listing, quoted exactly above.
- The pay is an annual base salary in US dollars with a minimum of at least $100,000.
- The role was publicly listed on the employer's job board when last checked.
We do not verify what the employer will actually offer, whether the employer is still recruiting for the role, or anything beyond what the employer published. Full methodology.
