Senior Scientist/Team Leader – Bioprocess Development
Company websiteecolab.com (Ecolab, opens in new tab)
Base salary $107,600 to $161,500
Employer-published annual base salary, USD. Advertised base range in King of Prussia, PA
You apply on the employer's own site. Six Figure Work does not handle applications.
- LocationKing of Prussia, PA
- WorkplaceWorkplace not stated
- Status at last checkSource accepting applications when checked
- Last checked (59 min ago) · observed since
About this job
Senior Scientist/Team Leader – Bioprocess Development
About the Role
We are seeking a passionate and experienced Senior Scientist/Team Leader – Bioprocess Development to lead downstream process development team focused on the chromatographic purification of monoclonal antibodies (mAbs). This role is central to our mission of enabling large and small biopharmaceutical companies to bring transformative therapies to patients faster and more efficiently.
As a scientific leader, you will guide a team in designing and executing purification strategies that support late-stage development and manufacturing readiness. You’ll work closely with external biopharma clients, helping them advance their molecules toward commercialization—ultimately impacting patient lives around the world.
Key Responsibilities
- Lead a team of bioprocess development scientists and serve as a subject matter expert in monoclonal antibody downstream processing with a heavy focus on preparative chromatography. Partner with leaders across Ecolab’s global Bioprocessing labs to address complex purification challenges.
- Design, execute, and analyze chromatography-based purification processes for mAbs, including Protein A, ion exchange, HIC, and related modalities.
- Develop scalable, robust purification processes tailored to client molecules and manufacturing objectives.
- Lead technology transfer activities with external manufacturing partners.
- Prepare technical reports, protocols, and documentation to support regulatory submissions.
- Work directly with leading biopharma clients to align on study design, timelines, and deliverables.
- Deliver high-quality experimental data that supports client development programs and regulatory filings.
- Act as a trusted scientific partner, helping clients resolve technical challenges and accelerate progress toward commercialization.
- Manage daily lab operations, including equipment maintenance, inventory, and safety compliance.
- Mentor junior scientists and research associates, supporting their technical growth and execution excellence.
- Promote a culture of scientific rigor, operational discipline, and continuous improvement.
Minimum Qualifications
- M.S. in Biochemistry, Chemical Engineering, Biotechnology, or related field with 8+ years of relevant industry experience, or
- Ph.D. with 4+ years of experience in downstream process development for biologics.
- Demonstrated expertise in preparative chromatography and antibody purification.
- Proven ability to lead small scientific teams and manage lab operations.
- Sponsorship is not offer for this role
Preferred Qualifications
- Hands-on experience with AKTA systems, Unicorn software, and high-throughput screening platforms (e.g., Tecan Te-Chrom).
- Proficiency in analytical techniques such as HPLC, SDS-PAGE, ELISA, UV spectroscopy.
- Familiarity with tech transfer, cGMP/cGLP standards, and regulatory documentation.
- Experience in client-facing or CDMO environments is a plus.
- Strong communication, organizational, and problem-solving skills.
- Working knowledge of statistical tools (e.g., JMP,) and data analysis software
Why This Role Matters
This is more than a lab-based leadership role—it’s an opportunity to directly influence the development of biologic therapies that improve and save lives. You’ll be working with some of the world’s leading biopharma companies, helping them refine and scale their purification processes to bring innovative treatments to patients in need.
Annual or Hourly Compensation Range
The base salary range for this position is $107,600.00 - $161,500.00. This position is eligible for annual bonus pay based on performance, per plan terms. Many factors are taken into consideration when determining compensation, such as experience, education, training, geography, etc. We comply with all minimum wage and overtime laws.Benefits
Ecolab strives to provide comprehensive and market-competitive benefits to meet the needs of our associates and their families. Click here to see our benefits.
If you are viewing this posting on a site other than our Ecolab Career website, view our benefits at jobs.ecolab.com/working-here.
Potential Customer Requirements Notice
To meet customer requirements and comply with local or state regulations, applicants for certain customer-facing roles may need to:
- Undergo additional background screens and/or drug/alcohol testing for customer credentialing.
Americans with Disabilities Act (ADA)
Ecolab will provide reasonable accommodation (such as a qualified sign language interpreter or other personal assistance) with our application process upon request as required to comply with applicable laws. If you have a disability and require accommodation assistance in this application process, please visit the Recruiting Support link in the footer of each page of our career website.
Source: Ecolab on Workday · View original posting (opens in new tab)
Pay in context
This role's base floor ($107,600) is above 13% of the 46 Science & Research roles in Pennsylvania listed on this site. Their median floor is $146,688; the middle half runs from $117,000 to $176,600.
Only jobs on this site count, and each one publishes a base salary of $100,000 or more, so this compares six-figure jobs with each other, not with the whole market. Computed Nov 8, 2026.
This listingSenior Scientist/Team Leader – Bioprocess Development$107,600 to $161,500
Senior Marketing Communications Manager II$107,600 to $161,500
Lead Platform Engineer$107,600 to $161,500
Global Category Manager - Marketing Agency Procurement$107,600 to $161,500
EHS Manager$107,600 to $161,500
Quality and Compliance Regulated Software Systems$107,600 to $161,500
Customer Supply Chain Manager - North America$107,600 to $161,500
Chart as a table
| Role | Published base |
|---|---|
| Senior Scientist/Team Leader – Bioprocess Development (this listing) | $107,600 - $161,500 |
| Senior Marketing Communications Manager II | $107,600 - $161,500 |
| Lead Platform Engineer | $107,600 - $161,500 |
| Global Category Manager - Marketing Agency Procurement | $107,600 - $161,500 |
| EHS Manager | $107,600 - $161,500 |
| Quality and Compliance Regulated Software Systems | $107,600 - $161,500 |
| Customer Supply Chain Manager - North America | $107,600 - $161,500 |
Observed changes
- First observed on the employer's board
- Began meeting the published-salary criteria
- Observed since
- Employer-stated posting date
- 2026-08-20
Where this pay comes from
Location as the employer wrote it: USA - Pennsylvania - King of Prussia
The base salary range for this position is $107,600.00 - $161,500.00. This position is eligible for annual bonus pay based on pe
- Method
- Employer text, read with fixed rules and re-verified
- Checked
- Rule set
- us-base-v2
The pay passage appears in the employer's own job text. Fixed, deterministic rules located it, and the passage below was checked against the stored copy of the posting.
What we verified
- The pay figures come from the employer's own listing, quoted exactly above.
- The pay is an annual base salary in US dollars with a minimum of at least $100,000.
- The role was publicly listed on the employer's job board when last checked.
We do not verify what the employer will actually offer, whether the employer is still recruiting for the role, or anything beyond what the employer published. Full methodology.