Software Engineer I/II - Scientific Computing
Company websiteiambic.ai (Iambic Therapeutics, Inc, opens in new tab)
Base salary $152K to $190K
Employer-published annual base salary, USD. Advertised base range in Boston, MA
This opportunity has 2 location variants. Pay shown applies only to the location named; other locations may differ.
You apply on the employer's own site. Six Figure Work does not handle applications.
- LocationBoston, MA
- WorkplaceHybrid
- Status at last checkSource accepting applications when checked
- Last checked (2 h ago) · observed since
About this job
JOB SUMMARY
Iambic is seeking a Software Engineer to build software that helps computational chemists run, monitor, and analyze scientific workloads. You will join the Software Engineering group and work closely with computational chemists and machine learning researchers to turn research needs into reliable Python applications and cloud workflows. The role spans design, implementation, deployment, and support for software used in computational drug discovery. This full-time role is based on the US East Coast, ideally in Boston; remote work elsewhere in the United States is also considered.
KEY RESPONSIBILITIES
Partner closely with computational chemists and machine learning researchers to understand research needs and deliver practical software solutions.
Build and maintain Python applications, libraries, APIs, and command-line tools.
Develop reliable workflows for drug discovery workloads.
Improve orchestration, monitoring, and recovery for workloads on AWS and neo-clouds such as Modal and Lambda.
Integrate scientific applications with shared data, compute, and model services.
Troubleshoot issues, document tools, and help scientists use them effectively.
Contribute to design, testing, review, deployment, and production support.
QUALIFICATIONS
Bachelor's degree in a relevant technical field and five or more years of software development experience, or equivalent practical experience.
Strong Python skills and experience writing clear, tested, maintainable production code.
Experience running scientific or batch workloads on AWS.
Experience with Prefect or another workflow orchestration system.
Familiarity with computational chemistry workloads such as molecular dynamics or docking.
Familiarity with the machine learning model lifecycle
Strong service mindset, clear communication, and a genuine interest in helping scientists be effective.
ABOUT IAMBIC THERAPEUTICS
Iambic is a clinical-stage life-science and technology company developing novel medicines using its AI-driven discovery and development platform. Based in San Diego and founded in 2020, Iambic has assembled a world-class team that unites pioneering AI experts and experienced drug hunters. The Iambic platform has demonstrated delivery of new drug candidates to human clinical trials with unprecedented speed and across multiple target classes and mechanisms of action. Iambic is advancing a pipeline of potential best-in-class and first-in-class clinical assets, both internally and in partnership, to address urgent unmet patient need. Learn more about the Iambic team, platform, pipeline, and partnerships at iambic.ai.
MISSION & CORE VALUES
Our mission is to deliver better medicines through innovations in AI-based discovery technologies. The culture and work at Iambic Therapeutics are profoundly strengthened by the diversity of our people and our differences in background, culture, national origin, religion, sexual orientation, and life experiences. We are committed to building an inclusive environment where a diverse group of talented humans work together to discover therapeutics and create technologies.
PAY AND BENEFITS
We offer industry leading competitive pay, company paid healthcare, flexible spending accounts, voluntary life insurance, 401K matching, and uncapped vacation to our team. We are in a brand-new state-of-the art facility in beautiful San Diego with an onsite gym, dining, and easy access to great places to live and play.
Source: Iambic Therapeutics, Inc on Ashby · View original posting (opens in new tab)
Pay in context
This role's base floor ($152,000) is above 52% of the 393 Software Engineering roles in Massachusetts listed on this site. Their median floor is $150,000; the middle half runs from $134,250 to $172,000.
Only jobs on this site count, and each one publishes a base salary of $100,000 or more, so this compares six-figure jobs with each other, not with the whole market. Computed Nov 6, 2026.
This listingSoftware Engineer I/II - Scientific Computing$152K to $190K
Lead Clinical Data Manager$152K to $190K
Principal Medical Writer$152K to $190K
Corporate Counsel, Commercial$152K to $200K
Machine Learning Scientist – Clinical Prediction$148K to $186K
Associate Director, Procurement$156K to $195K
Research Scientist II/Senior, Discovery Machine Learning$146,400 to $183,000
Chart as a table
| Role | Published base |
|---|---|
| Software Engineer I/II - Scientific Computing (this listing) | $152K - $190K |
| Lead Clinical Data Manager | $152K - $190K |
| Principal Medical Writer | $152K - $190K |
| Corporate Counsel, Commercial | $152K - $200K |
| Machine Learning Scientist – Clinical Prediction | $148K - $186K |
| Associate Director, Procurement | $156K - $195K |
| Research Scientist II/Senior, Discovery Machine Learning | $146,400 - $183,000 |
Observed changes
- Began meeting the published-salary criteria
- First observed on the employer's board
- Began meeting the published-salary criteria
- Observed since
- Employer-stated posting date
- 2026-09-25
Where this pay comes from
$152K - $190K in Boston, MA
Location as the employer wrote it: Software Engineer II
USD 152,000 – 190,000 · 1 YEAR · Salary · Software Engineer II
- Method
- Structured pay field published by the employer
- Checked
- Rule set
- us-base-v2
The employer's job board publishes this pay as a dedicated data field. We read the field directly; no interpretation was needed.
$129K - $162K in Boston, MA
Location as the employer wrote it: Software Engineer I
USD 129,000 – 162,000 · 1 YEAR · Salary · Software Engineer I
- Method
- Structured pay field published by the employer
- Checked
- Rule set
- us-base-v2
The employer's job board publishes this pay as a dedicated data field. We read the field directly; no interpretation was needed.
What we verified
- The pay figures come from the employer's own listing, quoted exactly above.
- The pay is an annual base salary in US dollars with a minimum of at least $100,000.
- The role was publicly listed on the employer's job board when last checked.
We do not verify what the employer will actually offer, whether the employer is still recruiting for the role, or anything beyond what the employer published. Full methodology.