Technical Development Principal Scientist / Engineer
Company websiteroche.com (Roche, opens in new tab)
Base salary $120,800 to $224,300
Employer-published annual base salary, USD. Advertised base range in South San Francisco, CA
You apply on the employer's own site. Six Figure Work does not handle applications.
- LocationSouth San Francisco, CA
- WorkplaceWorkplace not stated
- Status at last checkSource accepting applications when checked
- Last checked (1 h ago) · observed since
About this job
A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Genentech, a member of the Roche group!
In Pharma Technical Development (PTD), we actively collaborate and develop creative technical solutions to efficiently transform scientific ideas into products. Our mission is to reliably deliver the pipeline and supply quality products to patients. The group excels in its work through innovation, teamwork, dedication and mutual respect, and contributes every single day, continuously improving what it does.
The Opportunity
A Principal Engineer / Scientist position is available in Genentech and Roche’s Pharma Technical Development organization within the Cell Culture and Bioprocess Operations (CCBO) group.
Job Responsibilities:
- Serve as a key team member in developing scalable, robust, efficient, and sustainable microbial (E. coli) processes for biologics production.
- Represent the function on cross-functional project teams, collaborating with leads on all aspects of CMC project deliverables.
- Stay informed on industry trends and advancements in microbial process technology.
- Collaborate with representatives across research, manufacturing, quality, and regulatory functions.
- Author sections of regulatory filings and prepare responses for Health Authority Q&A.
- Serve as a functional ambassador to advocate for and influence stakeholders on new technology implementation.
Who you are
Requirements:
- Advanced degree in Chemical Engineering or a related discipline, with a Master’s degree and 8+ years of relevant experience, or a Ph.D. with 4+ years of relevant experience in E. coli or other microbial process development.
- Advanced technical experience supporting E. coli or other microbial process development, characterization, and validation activities.
- Proven ability to work independently, challenge the status quo, manage multiple projects, prioritize and delegate effectively, adapt quickly to changes, and collaborate on cross-functional teams.
- Strong written and verbal communication skills.
Preferred:
- Biopharma industry experience.
- Experience developing and implementing models and leveraging AI-based tools for microbial process development and optimization.
- Experience in microbial media development.
Relocation benefits are available for this job posting.
The expected salary range for this position based on the primary location of South San Francisco, CA is $120,800 - $224,300. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
Benefits
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
Source: Roche on Workday · View original posting (opens in new tab)
This listingTechnical Development Principal Scientist / Engineer$120,800 to $224,300
Technical Development Principal Scientist - Cell Therapy Process Development$120,800 to $224,300
Senior Scientist- Translational PKPD$120,700 to $224,100
Associate Program Director, Commercial Regulatory Affairs (CORA)$120,200 to $223,200
Senior Manager, Analytical Sciences and Technology, CVRM$120,100 to $223,100
Senior Manager, QC Chemistry and Device Testing (CVRM)$120,100 to $223,100
Senior Manager, Microbiology (CVRM)$120,100 to $223,100
Chart as a table
| Role | Published base |
|---|---|
| Technical Development Principal Scientist / Engineer (this listing) | $120,800 - $224,300 |
| Technical Development Principal Scientist - Cell Therapy Process Development | $120,800 - $224,300 |
| Senior Scientist- Translational PKPD | $120,700 - $224,100 |
| Associate Program Director, Commercial Regulatory Affairs (CORA) | $120,200 - $223,200 |
| Senior Manager, Analytical Sciences and Technology, CVRM | $120,100 - $223,100 |
| Senior Manager, QC Chemistry and Device Testing (CVRM) | $120,100 - $223,100 |
| Senior Manager, Microbiology (CVRM) | $120,100 - $223,100 |
Observed changes
- Began meeting the published-salary criteria
- First observed on the employer's board
- Observed since
- Employer-stated posting date
- 2026-10-07
Where this pay comes from
Location as the employer wrote it: South San Francisco
The expected salary range for this position based on the primary location of South San Francisco, CA is $120,800 - $224,300. Actual pay will be determined based on experience, qualifi
- Method
- Employer text, read with fixed rules and re-verified
- Checked
- Rule set
- us-base-v2
The pay passage appears in the employer's own job text. Fixed, deterministic rules located it, and the passage below was checked against the stored copy of the posting.
What we verified
- The pay figures come from the employer's own listing, quoted exactly above.
- The pay is an annual base salary in US dollars with a minimum of at least $100,000.
- The role was publicly listed on the employer's job board when last checked.
We do not verify what the employer will actually offer, whether the employer is still recruiting for the role, or anything beyond what the employer published. Full methodology.