Six Figure Work

Director, Compensation, Benefits and HR Systems

Iambic Therapeutics, Inc

Company websiteiambic.ai (Iambic Therapeutics, Inc, opens in new tab)

Base salary $180K  to $225K

Employer-published annual base salary, USD. Advertised base range in San Diego, CA

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  • LocationSan Diego, CA
  • WorkplaceHybrid
  • Status at last checkSource accepting applications when checked
  • Last checked (29 min ago) · observed since

About this job

JOB SUMMARY

We are hiring a Director of Compensation, Benefits and HR Systems to join our growing Human Resources team at Iambic Therapeutic's. Reporting to the Head of HR, this role will lead the design, implementation and ongoing management of Iambic’s compensation, benefits and HR technology platforms. They will ensure our programs are competitive, scalable, compliant, and aligned with Iambic’s talent strategy and business objectives, supporting a rapidly growing biotech company. This role is based at our San Diego Headquarters.

KEY RESPONSIBILITIES

  • Lead the company’s compensation strategy and programs, including salary structures, job leveling, annual compensation reviews, bonus programs, equity guidelines, promotions, and market benchmarking.

  • Manage executive, employee and international compensation benchmarking

  • Oversee employee benefits programs, including health insurance, retirement, leave, wellness, and other benefit offerings; evaluate competitiveness, cost, and employee experience.

  • Lead annual benefits renewal and open enrollment processes and manage relationships with brokers, consultants, and benefit vendors.

  • Own HRIS strategy and administration, including PEO exit, ensuring systems, workflows, integrations, reporting, and data are accurate, efficient, and scalable.

  • Establish and maintain policies, controls, documentation, and governance across compensation, benefits, and HR systems.

  • Identify opportunities to automate and streamline HR processes and improve the employee and manager experience.

  • Stay current on market trends, regulatory requirements, and emerging practices in compensation, benefits, and HR technology.

QUALIFICATIONS

  • Bachelor’s degree in human resources, business administration, finance or related field, Certified Compensation Professional (CCP) preferred.

  • 12+ years of progressive HR experience with significant expertise in compensation, benefits, and/or HRIS, including experience leading total rewards programs.

  • Strong knowledge of compensation benchmarking, salary structures, incentive compensation, equity programs, and job architecture. International experience a plus

  • Experience managing U.S. benefits programs and working with brokers, consultants, and vendors.

  • Demonstrated HRIS expertise, including system implementation, optimization, reporting, and data governance.

  • Strong analytical skills with the ability to translate complex compensation and workforce data into actionable recommendations.

  • Experience partnering with senior executives, Finance, Legal, and HR leadership.

  • Strong project management skills and ability to manage multiple priorities in a fast-paced environment.

  • Experience with a successful transition off a PEO, standing up in-house payroll, benefits administration, and HR Systems preferred.

  • Experience in a high-growth, biotechnology, technology, or public-company environment preferred.

ABOUT IAMBIC THERAPEUTICS
Iambic Therapeutics (Nasdaq: IAM) is a technology and clinical-stage life sciences company headquartered in San Diego. By utilizing molecular superintelligence — integrating proprietary AI with automated, scalable chemistry and biology experimentation — our platform is designed to address the totality of drug discovery and development. At Iambic, we are building an engine that is designed to power the future of medicine. Learn more at iambic.ai.

MISSION & VALUES
Our mission is to make better technology for better medicines. Three values guide how we work:

  • Bold. We are courageous, take thoughtful risks, and approach challenges with tenacity.

  • Innovative. We are creative and find new solutions that deliver impact.

  • Collaborative. We respect one another and partner with integrity.

We value the range of perspectives our people bring, and we work to build an environment where every team member can contribute and grow.

PAY AND BENEFITS
The pay range for this role is listed above. Actual pay depends on factors including experience, skills, and location. Eligible employees in the U.S. receive company-paid medical coverage, flexible spending accounts, voluntary life insurance, 401(k) matching and flexible time off. We are in a brand-new state-of-the art facility in beautiful San Diego with a community gym, dining, and easy access to great places to live and play.

EQUAL OPPORTUNITY
Iambic is an equal opportunity employer. We consider all qualified applicants without regard to race, color, religion, sex, sexual orientation, gender identity or expression, national origin, ancestry, age, disability, medical condition, genetic information, marital status, veteran or military status, or any other characteristic protected by law.

Source: Iambic Therapeutics, Inc on Ashby · View original posting (opens in new tab)

Pay in context

This role's base floor ($180,000) is above 78% of the 533 HR & Recruiting roles in California listed on this site; 17 others list the same floor. Their median floor is $150,000; the middle half runs from $126,550 to $172,000.

Only jobs on this site count, and each one publishes a base salary of $100,000 or more, so this compares six-figure jobs with each other, not with the whole market. Computed Nov 7, 2026.

This range next to 6 other live Iambic Therapeutics, Inc roles with the nearest advertised base floor
Chart as a table
This range next to 6 other live Iambic Therapeutics, Inc roles with the nearest advertised base floor
RolePublished base
Director, Compensation, Benefits and HR Systems (this listing)$180K - $225K
Associate Director/Director, FP&A$180K - $225K
Associate Director, Drug Safety$164K - $205K
Associate Director, Procurement$156K - $195K
Lead Clinical Data Manager$152K - $190K
Software Engineer I/II - Scientific Computing$152K - $190K
Principal Medical Writer$152K - $190K

Same $100K to $400K scale as every card. All Iambic Therapeutics, Inc roles · How to read the bar

Observed changes

  1. Began meeting the published-salary criteria
  2. First observed on the employer's board
Observed since
Employer-stated posting date
2026-09-10
Where this pay comes from

Location as the employer wrote it: San Diego HQ

USD 180,000 – 225,000 · 1 YEAR · Salary

Method
Structured pay field published by the employer
Checked
Rule set
us-base-v2

The employer's job board publishes this pay as a dedicated data field. We read the field directly; no interpretation was needed.

What we verified

  • The pay figures come from the employer's own listing, quoted exactly above.
  • The pay is an annual base salary in US dollars with a minimum of at least $100,000.
  • The role was publicly listed on the employer's job board when last checked.

We do not verify what the employer will actually offer, whether the employer is still recruiting for the role, or anything beyond what the employer published. Full methodology.

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