Six Figure Work

Principal Analyst, Project Portfolio Management Technology

Vertex Pharmaceuticals

Company websitevrtx.com (Vertex Pharmaceuticals, opens in new tab)

Base salary $142,800  to $214,200

Employer-published annual base salary, USD. Advertised base range in Boston, MA

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  • LocationBoston, MA
  • WorkplaceWorkplace not stated
  • Status at last checkSource accepting applications when checked
  • Last checked (32 min ago) · observed since

About this job

Job Description

General Summary:

The Business Engagement & Technology Principal Analyst will be a technical resource in ensuring delivery and support of commercial-off-the-shelf (COTS) and a wide range of custom solutions in support of their business partners. The Business Engagement & Technology Principal Analyst will partner with business leadership to deliver capabilities and execute on a roadmap that align to support business strategy . Additionally, the Business Engagement & Technology Principal Analyst will maintain reliable, scalable and compliant systems that easily meet business needs by efficient delivery and enhancements that provides opportunities for developing and implementing innovative solutions and integrations.

Key Duties and Responsibilities:

  • Become a trusted partner of the business leaders within their remit
  • Understand their needs and vision, and deliver technology solutions to support and enable their goals and objectives
  • Provide insights on how technology can improve business processes to enable operating efficiencies and support the achievement of business goals and objectives.
  • Help refine and execute the technology strategy by leading the evaluation, selection, implementation, and ongoing maintenance of technology solutions.
  • Develop and maintain a long term life cycle plan for the ongoing maintenance and management of systems.
  • Manage relationships with our strategic software vendors and service providers
  • Work closely with DTE Compliance, Internal Audit, and Quality Assurance groups as needed to ensure compliance with all appropriate regulations, as well as our DTE system lifecycle and change management requirements

Knowledge and Skills:

  • In-depth knowledge in the core disciplines of project management, business analysis, solution design, delivery, and testing
  • Experienced in building productive partnerships with business stakeholders and aligning them around a recommendation/solution
  • Strong understanding of the business, processes, and any appropriate regulatory environments
  • Results oriented contributor with a proven track record of on-time project delivery for large, complex projects with global stakeholders
  • Able to manage own workload with minimal direction
  • Very strong written and verbal communication skills and strong ability to present complex or sensitive information in a clear and concise manner to various technical and non-technical audiences
  • Exceptional analytical, quantitative, problem-solving, and prioritization skills
  • Strong system life cycle expertise
  • Good knowledge of running IT managed services or outsourced/ offshore teams
  • Very strong MS Office skills, including MS Project Server & Visio, Excel and PowerPoint experience
  • Experience in Agile methodology

Education and Experience:

  • Bachelor's degree in technology discipline or equivalent
  • 6 years relevant business systems in the Life Sciences industry, or the equivalent combination of education and experience


#LI-HYBRID #LI-JS1


At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.

Pay Range:

$142,800 - $214,200

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.  From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as: 
1.    Hybrid: work remotely up to two days per week; or select
2.    On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. 

#LI-Hybrid
 

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [email protected]

Source: Vertex Pharmaceuticals on Workday · View original posting (opens in new tab)

Pay in context

This role's base floor ($142,800) is above 67% of the 106 IT & Security roles in Massachusetts listed on this site. Their median floor is $134,822; the middle half runs from $120,000 to $145,900.

Only jobs on this site count, and each one publishes a base salary of $100,000 or more, so this compares six-figure jobs with each other, not with the whole market. Computed Nov 8, 2026.

This range next to 6 other live Vertex Pharmaceuticals roles with the nearest advertised base floor
Chart as a table
This range next to 6 other live Vertex Pharmaceuticals roles with the nearest advertised base floor
RolePublished base
Principal Analyst, Project Portfolio Management Technology (this listing)$142,800 - $214,200
Principal Scientist, Aseptic Control - MSAT Process$145,500 - $218,300
Strategic Sourcing Associate Director$145,600 - $218,400
Optics / Microscopy Principal Scientist$144,400 - $216,600
Principal Engineer, Microsoft 365 and Copilot Platforms$144K - $216K
Analytics CoE Senior Manager$144K - $216K
CDP/MA/OneTrust Operations Sr. Manager$144K - $216K

Same $100K to $400K scale as every card. All Vertex Pharmaceuticals roles · How to read the bar

Observed changes

  1. First observed on the employer's board
  2. Began meeting the published-salary criteria
Observed since
Employer-stated posting date
2026-09-15
Where this pay comes from

Location as the employer wrote it: Boston, MA

$142,800 - $214,200

Method
Employer text, read with fixed rules and re-verified
Checked
Rule set
us-base-v2

The pay passage appears in the employer's own job text. Fixed, deterministic rules located it, and the passage below was checked against the stored copy of the posting.

What we verified

  • The pay figures come from the employer's own listing, quoted exactly above.
  • The pay is an annual base salary in US dollars with a minimum of at least $100,000.
  • The role was publicly listed on the employer's job board when last checked.

We do not verify what the employer will actually offer, whether the employer is still recruiting for the role, or anything beyond what the employer published. Full methodology.

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