Senior Director, Global Oncology RWD Platform

Join a Growing Team that is Advancing the use of real world data in support of one of the largest oncology portfolios in the industry.

AstraZeneca’s Evidence Generation to Publications (EG2P) team is currently building APOLLO (AZ Partnerships in Oncology Leveraging real world evidence), a global oncology real world data (RWD) platform to support

Oncology Evidence Generation. In the first year of a 5+ year program, APOLLO already brings together 5 data partners across 11 markets and 3 tumor types to support insight discovery, medical strategy and publication grade evidence generation, and has gained substantial traction across global, regional and local functions within AZ.

Reporting to the Head, NextGen Sciences, as Senior Director, you will be the scientific lead for the platform’s future. You will drive expansion of APOLLO across geographies, tumor areas and/or use cases; shape the partner strategy, and communicate the value of accessing RWD through APOLLO across the entire Oncology Business Unit (OBU).

If you are an RWE leader who combines hands-on technical depth with the ability to explain the value of RWD clearly to senior audiences, this role is built for you.

What you will do

Set the data strategy: own the roadmap for APOLLO’s future, including which sources, markets and tumour types come next, and how the platform supports insight, strategy and evidence use cases.

Identify and Assess future data partners: appraise candidate data sources, including structure, completeness, provenance and suitability for regulatory-grade or publication-grade use, and decide the future direction of data, beyond traditional RWD to true multi-modal data for the entire organization.

Build the partner ecosystem: identify, evaluate and negotiate with data partners worldwide, especially in markets where oncology RWD is limited, working with global RWD leaders to create new data assets.

Advance the science: assess and pilot new approaches to RWD collection and curation, including AI/NLP- enabled abstraction from unstructured EHR data, and set the standard for how they are validated.

Be the voice of APOLLO: explain the platform's value and limits to all parts of the OBU, senior leaders and external experts. You will define what stakeholders hear, from clear guidance and dashboards to conference and publication presence.

Lead through influence: lead a matrix team across EG2P and the wider Oncology Business Unit, and mentor colleagues to build RWE capability.

Keep it compliant: ensure all activity meets AstraZeneca standards, standard operating procedures (SOPs) and external regulations.

Your Impact on Global Cancer Care

This isn't just a role, it is your opportunity to directly influence AstraZeneca's entire oncology portfolio. You will unlock unprecedented access to real-world treatment patterns and patient outcomes across key tumor types globally, providing the evidence foundation that shapes tomorrow's cancer treatments.

Drive Innovation at Scale

Join a highly innovative, motivated and growing team at the cutting edge of evidence generation. As Senior Director of Global Oncology RWD Platform, you'll pioneer the development of next-generation data solutions and implement breakthrough approaches that deliver timely, impactful real-world evidence across AstraZeneca's comprehensive oncology pipeline.

Ready to lead the data revolution that will transform cancer care worldwide? This is where your expertise meets extraordinary impact.

Typical Accountabilities:

The Senior Director, Global Oncology RWD Platform will:

• Work with the broader NextGen Sciences (NGS) team to shape and communicate APOLLO’s future to AZ Oncology stakeholders.
• Identify and assess potential new partners for potential inclusion in APOLLO and conduct feasibility assessments to ensure fit for purpose with APOLLO strategy of expanding access to real world oncology data.
• Develop and implement a Roadmap to support APOLLO’s continued growth.
• Participate in Integrated Evidence Plan (IEP) development to identify opportunities for APOLLO utilization.
• Work with global RWD leaders to develop new data assets, particularly in markets where significant oncology RWD gaps currently exist.
• Create and execute strategies that drive the implementation of APOLLO, ensuring availability of timely and meaningful data to support AZ’s global oncology real world evidence needs.
• Foster collaborative relationships with external experts to help shape future APOLLO initiatives.
• Provide leadership and mentoring to teams and individuals to upskill and develop future capabilities in line with AstraZeneca’s dedication to a culture of performance development and lifelong learning.
• Ensure that all Medical and business activities are carried out in compliance with AZ standards, (SOPs), and external regulations.
• Office based position, <10% travel required

Essential Qualifications

• Advanced degree (MSc, PharmD, PhD orequivalent) in epidemiology, outcomes research, statistics, health economics or a related field.
• 10+ years in RWE or RWD, in pharma, biotech, data or analytics company, consulting or academia, including building or governing RWD assets.
• Deep expertise in real world research methods, pharmacoepidemiology and HEOR, and the judgment to define data structure and inclusion criteria for several use cases.
• Oncology RWE experience across multiple tumour types· Hands-on experience applying tools for curation and abstraction of unstructured EHR data.

Desirable Qualifications

• PhD in a relevant discipline.
• A track record of negotiating or managing external data partnerships.
• Knowledge of current regulatory and HTA expectations for RWE.
• Experience with dashboards or data visualisation tools for non-technical users.
• Demonstrated leadership and management experience, including effective problem and conflict resolution skills and validated team focus.

The annual base pay (or hourly rate of compensation) for this position ranges from $229,047 to $343,570. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

Date Posted

02-Nov-2026

Closing Date

01-Nov-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.