Six Figure Work

Senior Principal, Source to Pay Technology

Vertex Pharmaceuticals

Company websitevrtx.com (Vertex Pharmaceuticals, opens in new tab)

Base salary $177,600  to $266,400

Employer-published annual base salary, USD. Advertised base range in Boston, MA

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  • LocationBoston, MA
  • WorkplaceWorkplace not stated
  • Status at last checkSource accepting applications when checked
  • Last checked (26 min ago) · observed since

About this job

Job Description

General Summary:

The Senior Principal, Source to Pay Technology will provide technical expertise, delivery, and support for Source-to-Pay AI-powered technologies. This role will focus on the implementation and subsequent maintenance of Source to Pay Orchestration solutions and AI capabilities. This role will partner with business leadership to identify and prioritize opportunities to improve business processes with innovative technology and data, gathering and refining requirements, determining options for solution design, delivering enhancements, supporting integrations, and contributing to technology projects and initiatives.

Key Duties and Responsibilities:

  • Serve as a trusted advisor for business stakeholders on Source to Pay technology and AI solutions to support and enable the business goals and objectives

  • Collaborate with business stakeholders to understand their current and future state strategy, needs, and requirements from a global perspective

  • Implement AI capabilities in the Source to Pay space while meeting compliance, legal, and ethical standards, including data privacy and regulatory requirements

  • Proactively offer innovative technologies and solution ideas, and potential business process improvements in pursuit of driving efficiencies and meeting business needs

  • Facilitate workshops and discussions to collect and document user stories / requirements

  • Develop and document functional and technical aspects for integrations with upstream and downstream platforms

  • Design, perform and document system configurations within in-scope platforms and applications

  • Contribute to the creation and documentation of testing strategies and execution plans

  • Work with offshore team members and peers for platform support and technical development of enhancements and projects

  • Manage relationships with strategic software vendors and managed service providers (as needed)

  • Work closely with Privacy, DTE Compliance, and Internal Audit to ensure compliance with all appropriate regulations, data integrity policies, and Vertex’s system lifecycle and change management processes

Knowledge and Skills:

  • Experience with Source to Pay technologies (e.g., Contract Lifecycle Management platform (Icertis), Third-Party Risk Management platform (ProcessUnity), Electronic Signature platform (Docusign), Procure-to-Pay platform (Coupa), and Source to Pay Orchestration tools)

  • In-depth knowledge and hands-on experience implementing AI/ML technologies 

  • Demonstrated ability to translate business challenges into AI-driven solutions with measurable outcomes

  • Functional and technical expertise with application configurations, integrations, and documentation

  • Demonstrated ability to understand, analyze, and document complex business processes, translate business needs and functional requirements into technical or process-driven solutions

  • Self-directed individual who is able to work independently and collaboratively in a matrixed team environment

  • Experience in program and project management, demand management, resource management and system lifecycle management

  • Results-oriented individual with a proven track record of on-time project delivery for large, complex projects with global stakeholders

  • Exceptional analytical, quantitative, problem-solving, and prioritization skills

  • In-depth experience in design, development, and deployment of technology solutions using agile software development practices and dev/ops model

  • Very strong written and verbal communication skills and ability to present in a clear and concise manner to various technical and non-technical audiences

  • Demonstrated ability to solve complex business problems by collaborating across organizational boundaries

Education and Experience:

  • Bachelor's degree in technology discipline or equivalent

  • 8+ years of work experience with relevant business systems in the Life Sciences industry, or the equivalent combination of education and experience

  • Experience working with implementation partners as well as managed services providers and/or offshore teams

  • Preferred experience with ZipHQ

#LI-HYBRID


At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.

Pay Range:

$177,600 - $266,400

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations.  From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as: 
1.    Hybrid: work remotely up to two days per week; or select
2.    On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. 

#LI-Hybrid
 

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [email protected]

Source: Vertex Pharmaceuticals on Workday · View original posting (opens in new tab)

This range next to 6 other live Vertex Pharmaceuticals roles with the nearest advertised base floor
Chart as a table
This range next to 6 other live Vertex Pharmaceuticals roles with the nearest advertised base floor
RolePublished base
Senior Principal, Source to Pay Technology (this listing)$177,600 - $266,400
Director, Marketing Operations$180K - $270K
Biostatistics Associate Director (HYBRID)$174,800 - $262,200
Biostatistics Associate Director (HYBRID)$174,800 - $262,200
Director, Disease Strategy Finance$180,700 - $271,100
Director, Financial Planning & Analysis - R&D$180,700 - $271,100
Real World Evidence Associate Director$174,400 - $261,600

Same $100K to $400K scale as every card. All Vertex Pharmaceuticals roles · How to read the bar

Observed changes

  1. First observed on the employer's board
  2. Began meeting the published-salary criteria
Observed since
Employer-stated posting date
2026-09-08
Where this pay comes from

Location as the employer wrote it: Boston, MA

$177,600 - $266,400

Method
Employer text, read with fixed rules and re-verified
Checked
Rule set
us-base-v2

The pay passage appears in the employer's own job text. Fixed, deterministic rules located it, and the passage below was checked against the stored copy of the posting.

What we verified

  • The pay figures come from the employer's own listing, quoted exactly above.
  • The pay is an annual base salary in US dollars with a minimum of at least $100,000.
  • The role was publicly listed on the employer's job board when last checked.

We do not verify what the employer will actually offer, whether the employer is still recruiting for the role, or anything beyond what the employer published. Full methodology.