Senior Scientist - PKDM-BA
Company websiteamgen.com (Amgen, opens in new tab)
Base salary $143,821 to $194,581
Employer-published annual base salary, USD. Advertised base range in South San Francisco, CA
You apply on the employer's own site. Six Figure Work does not handle applications.
- LocationSouth San Francisco, CA
- WorkplaceOn-site
- Status at last checkSource accepting applications when checked
- Last checked (1 h ago) · observed since
About this job
Career Category
ResearchJob Description
Join Amgen’s Mission of Serving Patients
At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.
Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.
Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.
Senior Scientist - PKDM-BA
What you will do
Let’s do this. Let’s change the world. The responsibilities of the successful candidate will be to design and execute biological and/or biophysical experiments to understand the ADME properties of large molecule therapeutics (and non-traditional small molecule therapies) in support of both drug discovery and early development programs.
This is a lab-based role, with an emphasis on assay/technology development for the purposes of defining mechanisms of in vivo clearance and/or biodistribution processes. This role requires an understanding of preclinical ADME and bioanalytical techniques and an individual that can work collaboratively in a fast-paced work environment.
Other responsibilities include data interpretation and communication of results to project team representatives and electronic laboratory notebook keeping of results. The candidate may also be responsible for developing and executing department strategy for drug candidate teams as a PKDM project representative.
What we expect of you
We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a scientist with these qualifications.
Basic Qualifications:
Doctorate degree PhD OR PharmD OR MD [and relevant post-doc where applicable]
OR
Master’s degree and 3 years of related experience
OR
Bachelor’s degree and 5 years of related experience
Preferred Qualifications:
- PhD or MS in immunology, cell biology, biochemistry, biophysics, or equivalent.
- 2+ years of protein therapeutics drug discovery and development experience in biotech industry, basic understanding of protein therapeutics pharmacokinetics.
- Expertise, and a strong interest in evaluating protein-protein interactions using modern biophysical analytic techniques.
- Expertise in protein biochemistry and/or cell biology techniques, including reagent preparation, assay development, optimization and troubleshooting.
- Experience translating biochemical and biophysical observations and phenomena into relevant cellular and animal-based models with mechanistic insights is desirable.
- Excellent communication and interpersonal skills and the ability and interest to learn and deliver results in a fast-paced, demanding environment.
What you can expect from us
As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.
The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:
- A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
- A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
- Stock-based long-term incentives
- Award-winning time-off plans
- Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.
Apply now and make a lasting impact with the Amgen team.
careers.amgen.com
In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.
Application deadline
Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.
Sponsorship
Sponsorship for this role is not guaranteed.
As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.
Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance.Salary Range
143,820.85USD -194,581.15 USDSource: Amgen on Workday · View original posting (opens in new tab)
Pay in context
This role's base floor ($143,821) is above 39% of the 492 Science & Research roles in California listed on this site; 1 other lists the same floor. Their median floor is $158,777; the middle half runs from $126,066 to $200,000.
Only jobs on this site count, and each one publishes a base salary of $100,000 or more, so this compares six-figure jobs with each other, not with the whole market. Computed Nov 8, 2026.
This listingSenior Scientist - PKDM-BA$143,821 to $194,581
Senior Manager, Manufacturing Systems Engineering (ASRS)$145,370 to $196,676
Field Reimbursement Manager - Miami, FL$145,471 to $196,813
Field Reimbursement Manager - Newark, NJ$145,471 to $196,813
Field Reimbursement Manager- Cleveland, Ohio$145,471 to $196,813
Field Reimbursement Manager- Portland, OR$145,471 to $196,813
Field Reimbursement Manager - New York Metro$145,471 to $196,813
Chart as a table
| Role | Published base |
|---|---|
| Senior Scientist - PKDM-BA (this listing) | $143,821 - $194,581 |
| Senior Manager, Manufacturing Systems Engineering (ASRS) | $145,370 - $196,676 |
| Field Reimbursement Manager - Miami, FL | $145,471 - $196,813 |
| Field Reimbursement Manager - Newark, NJ | $145,471 - $196,813 |
| Field Reimbursement Manager- Cleveland, Ohio | $145,471 - $196,813 |
| Field Reimbursement Manager- Portland, OR | $145,471 - $196,813 |
| Field Reimbursement Manager - New York Metro | $145,471 - $196,813 |
Observed changes
- First observed on the employer's board
- Began meeting the published-salary criteria
- Observed since
- Employer-stated posting date
- 2026-09-23
Where this pay comes from
Location as the employer wrote it: US - California - South San Francisco
143,820.85USD -194,581.15 USD
- Method
- Employer text, read with fixed rules and re-verified
- Checked
- Rule set
- us-base-v2
The pay passage appears in the employer's own job text. Fixed, deterministic rules located it, and the passage below was checked against the stored copy of the posting.
What we verified
- The pay figures come from the employer's own listing, quoted exactly above.
- The pay is an annual base salary in US dollars with a minimum of at least $100,000.
- The role was publicly listed on the employer's job board when last checked.
We do not verify what the employer will actually offer, whether the employer is still recruiting for the role, or anything beyond what the employer published. Full methodology.
