Clinical Development Medical Director, Early Development – Cardiometabolic
Company websiteamgen.com (Amgen, opens in new tab)
Base salary $274,789 to $371,773
Employer-published annual base salary, USD. Advertised base range in United States
You apply on the employer's own site. Six Figure Work does not handle applications.
- LocationUnited States
- WorkplaceRemote
- Status at last checkSource accepting applications when checked
- Last checked (1 h ago) · observed since
About this job
Career Category
Clinical DevelopmentJob Description
Join Amgen’s Mission of Serving Patients
At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.
Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.
Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.
Clinical Development Director
What you will do
Let’s do this. Let’s change the world. In this vital role, you will lead the early phase clinical development of compounds from first-in-human studies through proof-of-concept. You will collaborate on teams to support the design and delivery of early phase clinical trials. Through this role, the Clinical Medical Director will support protocol development, study start up, data review, monitoring and analysis activities.
Responsibilities
- Contribute to the design and implementation of the early clinical development strategy for cardiometabolic/general medicine therapeutic candidates
- Contribute to the preparation of clinical development plans, clinical study protocols, informed consents, Investigator Brochures, and Ethics Committee and regulatory agency submissions
- Review and evaluate clinical study safety, efficacy, pharmacodynamic and pharmacokinetic data
- Contribute to the strategy and use of clinical biomarkers to facilitate drug development
- Actively collaborate with Amgen Precision Medicine, Research, Late Development, Regulatory, Safety and Commercial colleagues
- Contribute to the evaluation of external licensing or partnering opportunities within the cardiometabolic/general medicine therapeutic areas
- Collaborate with external experts to provide biomedical expertise and strategic guidance to cardiometabolic/general medicine Early Development teams
What we expect of you
We are all different, yet we all use our unique contributions to serve patients. The Early Development professional we seek is a Leader with these qualifications.
Basic Qualifications:
MD or DO degree from an accredited medical school AND
2 years of industry or academic/basic sciences/clinical research experience
Preferred Qualifications:
- Board certification or eligible
- Residency training in Cardiology, Internal Medicine or relevant subspecialty
- Understanding of cardiometabolic and general medicine pathophysiology
- Experience in basic research and/or clinical trial methodology
- 4+ years of relevant drug development experience in the pharmaceutical industry and/or academia, preferably in early stage clinical trials
- Experience collaborating with pharmaceutical sponsors
- Experience in designing, monitoring and implementing clinical trials and interpreting trial results
- Demonstrated leadership qualities; capable of conducting studies as part of a team
- Experience within a matrix environment, contributes to decision-making and reaching alignment in order to meet challenging timelines
- Publication track record
- Excellent interpersonal and presentation skills; able to communicate effectively with internal stakeholders, as well as external partners and collaborators
What you can expect of us
As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.
The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:
- A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
- A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
- Stock-based long-term incentives
- Award-winning time-off plans
- Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.
Apply now and make a lasting impact with the Amgen team.
careers.amgen.com
In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.
Application deadline
Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.
Sponsorship
Sponsorship for this role is not guaranteed.
As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
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Salary Range
274,788.85USD -371,773.15 USDSource: Amgen on Workday · View original posting (opens in new tab)
Pay in context
This role's base floor ($274,789) is above 76% of the 3,847 Healthcare Clinical roles nationwide listed on this site; 2 others list the same floor. Their median floor is $185,498; the middle half runs from $124,308 to $263,102.
Only jobs on this site count, and each one publishes a base salary of $100,000 or more, so this compares six-figure jobs with each other, not with the whole market. Computed Nov 8, 2026.
This listingClinical Development Medical Director, Early Development – Cardiometabolic$274,789 to $371,773
Clinical Development Medical Director, Early Development Oncology$274,789 to $371,773
Clinical Development Director, Early Development – Inflammation/Rare Disease$274,789 to $371,773
Clinical Development Medical Director, Obesity and Related Conditions$274,789 to $371,773
Biostatistics Oncology TA Head$267,393 to $361,767
Global Safety Medical Director, Rare Disease$256,607 to $347,174
Global Safety Medical Director$256,607 to $347,174
Chart as a table
| Role | Published base |
|---|---|
| Clinical Development Medical Director, Early Development – Cardiometabolic (this listing) | $274,789 - $371,773 |
| Clinical Development Medical Director, Early Development Oncology | $274,789 - $371,773 |
| Clinical Development Director, Early Development – Inflammation/Rare Disease | $274,789 - $371,773 |
| Clinical Development Medical Director, Obesity and Related Conditions | $274,789 - $371,773 |
| Biostatistics Oncology TA Head | $267,393 - $361,767 |
| Global Safety Medical Director, Rare Disease | $256,607 - $347,174 |
| Global Safety Medical Director | $256,607 - $347,174 |
Observed changes
- First observed on the employer's board
- Absent from the employer's board; confirmation pending
- Closure observed on Oct 15, 2026
- Reappeared on the employer's board
- fields changed
- Began meeting the published-salary criteria
- Observed since
- Employer-stated posting date
- 2026-10-16
Where this pay comes from
Location as the employer wrote it: United States - Remote
274,788.85USD -371,773.15 USD
- Method
- Employer text, read with fixed rules and re-verified
- Checked
- Rule set
- us-base-v2
The pay passage appears in the employer's own job text. Fixed, deterministic rules located it, and the passage below was checked against the stored copy of the posting.
What we verified
- The pay figures come from the employer's own listing, quoted exactly above.
- The pay is an annual base salary in US dollars with a minimum of at least $100,000.
- The role was publicly listed on the employer's job board when last checked.
We do not verify what the employer will actually offer, whether the employer is still recruiting for the role, or anything beyond what the employer published. Full methodology.