Integrated Safety Analysis (ISA) Engineer
Company websitegeneralmatter.com (General Matter, opens in new tab)
Base salary $100K to $200K
Employer-published annual base salary, USD. Advertised base range in Los Angeles, CA
You apply on the employer's own site. Six Figure Work does not handle applications.
- LocationLos Angeles, CA
- WorkplaceWorkplace not stated
- Status at last checkSource accepting applications when checked
- Last checked (3 h ago) · observed since
About this job
About This Role
As an ISA Engineer at General Matter, you will build the safety basis for a new NRC-licensed enrichment facility under 10 CFR Part 70. You will not inherit a 20-year-old ISA Summary and run change packages. You will develop the hazard analyses, accident sequences, and IROFS from the ground up, and your conclusions will shape the design while it is still on the drawing board. You will work directly with process, controls, and operations engineers, and you will be a technical voice in our NRC interactions. This is a mission of national importance, and few engineers get to take a Part 70 safety basis from a blank page through license application and into operation.
If you seek high impact and are excited by fast-paced, intense, Skunkworks-style projects, we encourage you to apply to join our team.
Responsibilities
- Own and develop Integrated Safety Analyses per 10 CFR Part 70 Subpart H and NUREG-1520, including hazard identification, accident sequence development, consequence analysis, and likelihood evaluation.
- Lead process hazard analyses (HAZOP, What-If, FMEA) with design and operations teams, and drive the resulting actions to closure.
- Define, evaluate, and maintain IROFS and management measures, and work with designers to favor inherently safer process choices over layered administrative controls.
- Develop and maintain the ISA Summary, safety basis change packages, and supporting technical analyses for the license application.
- Assess risks across nuclear criticality safety, chemical hazards (including UF6 and process chemicals), fire protection, and natural phenomena and external hazards.
- Support NRC interactions, including audits, inspections, and responses to requests for additional information.
- Participate in design verification, configuration management, and change control for modifications that affect the safety basis.
- Support startup, commissioning, and operational readiness as the facility moves from design to operation.
Basic Qualifications
- Bachelor’s degree in Chemical, Mechanical, or Nuclear Engineering, or a related field. An MS, MBA, or PhD may substitute for 2–3 years of experience, depending on degree level.
- 4+ years of experience in nuclear safety, process safety, or similar high-hazard environments.
- Working knowledge of safety analysis methods such as PHA, Criticality Safety Analysis, Fire Hazard Analysis, and External Hazard Analysis.
- Evidence of exceptional ability (prior projects, portfolio of work, completed products, etc.).
- Strong analytical skills and attention to detail, and the ability to explain technical safety conclusions clearly, in writing and in person, to engineers, operators, and regulators.
- Ability to work collaboratively across engineering, operations, and licensing teams.
Preferred Skills and Experience
- 8+ years of experience in nuclear safety, process safety, or similar high-hazard environments.
- Direct experience with ISA, ISA Summaries, IROFS, SARs, and risk determination at a Part 70 facility, or with DSA/SAR work under DOE 10 CFR 830.
- Experience with an NRC Part 70 license application or RAI responses.
- Petrochemical or PSM experience (HAZOP, LOPA, SIL). This is a strong substitute for nuclear experience, and we know the methods transfer.
- Knowledge of UF6 hazards, vacuum systems, cryogenics, compressible flow, or nuclear chemical processes.
- Experience in a fast-paced, resource-constrained environment where a resourceful, entrepreneurial approach was required to meet tight timelines.
- Familiarity with NRC safety standards and the associated regulatory framework.
Additional Requirements
- Ability to work extended hours and weekends as necessary.
Equal Opportunity Employer
General Matter is an Equal Opportunity Employer; employment with General Matter is governed on the basis of merit, competence and qualifications and will not be influenced in any manner by race, color, religion, gender, national origin/ethnicity, veteran status, disability status, age, sexual orientation, gender identity, marital status, mental or physical disability or any other legally protected status.
Compensation and Benefits
The base salary range for this role is $100,000–$200,000 annually.
Compensation bands are determined by role, level, location, and alignment with market data. Individual level and base pay is determined on a case-by-case basis and may vary based on job-related skills, education, experience, technical capabilities and internal equity. Please note that the stated salary range is an estimate and may be adjusted based on market conditions, business needs, or other factors. In addition to base salary, for full-time hires, you may also be eligible for long-term incentives, in the form of stock options, and access to medical, vision & dental coverage as well as access to a 401(k) retirement plan.
Source: General Matter on Greenhouse · View original posting (opens in new tab)
This listingIntegrated Safety Analysis (ISA) Engineer$100K to $200K
Business & Operations Recruiter$100K to $200K
IT Manager$100K to $160K
DevOps / Site Reliability Engineer$100K to $200K
Software Engineer, Hardware Test & Automation$100K to $200K
Technical Recruiter, Hardware Engineering$100K to $180K
Software Engineer$100K to $200K
Chart as a table
| Role | Published base |
|---|---|
| Integrated Safety Analysis (ISA) Engineer (this listing) | $100K - $200K |
| Business & Operations Recruiter | $100K - $200K |
| IT Manager | $100K - $160K |
| DevOps / Site Reliability Engineer | $100K - $200K |
| Software Engineer, Hardware Test & Automation | $100K - $200K |
| Technical Recruiter, Hardware Engineering | $100K - $180K |
| Software Engineer | $100K - $200K |
Observed changes
- Began meeting the published-salary criteria
- First observed on the employer's board
- Observed since
- Employer-stated posting date
- 2026-04-09
Where this pay comes from
Location as the employer wrote it: Los Angeles, CA
The base salary range for this role is $100,000–$200,000 annually.
- Method
- Employer text, read with fixed rules and re-verified
- Checked
- Rule set
- us-base-v2
The pay passage appears in the employer's own job text. Fixed, deterministic rules located it, and the passage below was checked against the stored copy of the posting.
What we verified
- The pay figures come from the employer's own listing, quoted exactly above.
- The pay is an annual base salary in US dollars with a minimum of at least $100,000.
- The role was publicly listed on the employer's job board when last checked.
We do not verify what the employer will actually offer, whether the employer is still recruiting for the role, or anything beyond what the employer published. Full methodology.
