Portfolio Leader
Company websiteroche.com (Roche, opens in new tab)
Base salary $149,300 to $277,300
Employer-published annual base salary, USD. Advertised base range in South San Francisco, CA +1 more
You apply on the employer's own site. Six Figure Work does not handle applications.
- LocationSouth San Francisco, CA +1 more
- WorkplaceWorkplace not stated
- Status at last checkSource accepting applications when checked
- Last checked (36 min ago) · observed since
All places named
- South San Francisco, CA
- Basel
About this job
At Roche/Genentech, we have a bold Pharma Ambition to deliver 20 transformative medicines addressing diseases with the highest societal burden by 2030. With this vision top of mind, our purpose is to co-create and deliver the target portfolio for the benefit of patients.
We want you to join our vision and be part of our passionate, collaborative, global Portfolio Strategy & Management (PSM) community! We are a strong, close, trusting community that lives new ways of working and operates from a creative mentality. We are THE place for talent to grow and contribute; our talent feels valued, connected, and a sense of belonging to something impactful. We have high impact; customers draw on our expertise to help them deliver the target portfolio more effectively/efficiently. We stop lower-value work. We’re BOLD. We try things, openly discuss and learn from mistakes and failure, experiment and iterate to achieve our aspirations.
The Opportunity:
As Portfolio Leader you will focus on providing Portfolio Strategy, Portfolio Management and Portfolio Insights & Analytics to partners across Pharma and the Roche enterprise. You will be expected to closely collaborate with colleagues in relevant groups beyond PSM in co-creating deliverables. You will also be involved in the development and application of analytical tools, financial models, and data-driven insights to shape the Pharma portfolio.
Key accountabilities for team members include, but are not limited to, a combination of the following areas:
- Strategic investment analysis - Provide analytical expertise to evaluate strategic options, leveraging financial modeling (rNPV, scenario analysis, trade-off optimization) to quantify risk, asset value, and competitive positioning that guide capital allocation decisions.
- Strategy support - Partner with Pharma Leaders to co-create and deliver robust portfolio and business strategies that provide the scaffolding for Pharma portfolio decisions
- Portfolio assessments and presentations - Manage and communicate portfolio dynamics (risk, value, mix, competitive positioning etc.) to inform portfolio decisions and strategy updates. Develop portfolio content and actionable insights presented to Executive Leadership.
- Decision support and valuation - Active thought partner to teams and decision-makers including, defining/scoping of tactics to deliver on defined business strategies
- Decision management and ecosystem architecture - Ensure decision quality by architecting the path to a decision, the decision making model, and portfolio prioritization. Design/evolve advice seeking and fit-for-purpose engagement opportunities, and develop/evolve resources and guidance to support decision making and portfolio management.
- Insights & analytics - Design, develop and improve portfolio metrics, analytics, and dynamic visualizations that enable operational efficiency and optimal decision-making and targeted communications. In addition, provide and update guidance on valuation and risk methodologies used by teams and decision-makers. Key deliverables include quarterly Pharma Portfolio Reports, annual R&D performance benchmarking, business planning and ad hoc requests.
Who You Are
- Bachelor's degree in Biostatistics, Applied Mathematics, Finance, Data Science, Engineering, or a similar quantitative discipline; Advanced degree (MS, PhD, MBA) highly preferred
- Strong understanding of disease/drug development to translate competitive/industry insights into actions.
- You have strong experience using a combination of quantitative rigor and collaborative partnership across matrixed technical teams (including Finance, Data Science, and Informatics) to ensure strategic models are translated into actionable portfolio delivery.
- You apply financial modeling and decision analysis to guide portfolio management decisions in the pharma/biotech or similar industry
- You have proven experience with tools like Python, R, and Tableau to you automate analytical workflows and generate predictive portfolio insights
Preferred Qualifications
- You are a dedicated and passionate individual, driven by our shared purpose of co-creating and delivering the portfolio for the benefit of patients.
- You thrive in environments of ambiguity and collaboration where authority and accountability is distributed between all of the people involved and where advice seeking is foundational.
- You are an effective communicator who shares information transparently and strategically. You are comfortable with working out loud and the principles of iteration and experimentation, and are an active listener.
- You are a strategic thinker who connects traditional biopharma strategy with the latest technology-enabled quantitative analytics.
- You are an effective communicator capable of synthesizing complex probabilistic models into clear narratives that guide portfolio decision-makers and leadership.
Relocation benefits are not available for this posting
The expected salary range for this position based on the primary location of California is $149,300 - $277,300. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
Benefits
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
Source: Roche on Workday · View original posting (opens in new tab)
Pay in context
This role's base floor ($149,300) is above 47% of the 866 Finance & Accounting roles in California listed on this site. Their median floor is $150,000; the middle half runs from $121,675 to $185,000.
Only jobs on this site count, and each one publishes a base salary of $100,000 or more, so this compares six-figure jobs with each other, not with the whole market. Computed Nov 8, 2026.
This listingPortfolio Leader$149,300 to $277,300
88-50100317 Upper Campus Plant Engineer$150,000 to $168,500
Product Engineering Manager - Commercial Pharma US Targeting, Recommendation, Optimization and Measurement$149,700 to $278,100
Principal Scientist, Structural Biology$150,700 to $279,900
Director, MSAT (Drug Product)$151K to $281K
Principal Product Leader, Therapeutics Discovery$148,600 to $276,000
Principal Product Leader- Therapeutics Discovery$148,600 to $276,000
Chart as a table
| Role | Published base |
|---|---|
| Portfolio Leader (this listing) | $149,300 - $277,300 |
| 88-50100317 Upper Campus Plant Engineer | $150,000 - $168,500 |
| Product Engineering Manager - Commercial Pharma US Targeting, Recommendation, Optimization and Measurement | $149,700 - $278,100 |
| Principal Scientist, Structural Biology | $150,700 - $279,900 |
| Director, MSAT (Drug Product) | $151K - $281K |
| Principal Product Leader, Therapeutics Discovery | $148,600 - $276,000 |
| Principal Product Leader- Therapeutics Discovery | $148,600 - $276,000 |
Observed changes
- First observed on the employer's board
- Began meeting the published-salary criteria
- Observed since
- Employer-stated posting date
- 2026-10-16
Where this pay comes from
Location as the employer wrote it: South San Francisco • Basel
The expected salary range for this position based on the primary location of California is $149,300 - $277,300. Actual pay will be determined based on experience, qualifi
- Method
- Employer text, read with fixed rules and re-verified
- Checked
- Rule set
- us-base-v2
The pay passage appears in the employer's own job text. Fixed, deterministic rules located it, and the passage below was checked against the stored copy of the posting.
What we verified
- The pay figures come from the employer's own listing, quoted exactly above.
- The pay is an annual base salary in US dollars with a minimum of at least $100,000.
- The role was publicly listed on the employer's job board when last checked.
We do not verify what the employer will actually offer, whether the employer is still recruiting for the role, or anything beyond what the employer published. Full methodology.
