Six Figure Work

Senior Director, AI Enablement

McKesson

Company websitemckesson.com (McKesson, opens in new tab)

Base salary $174,800  to $291,300

Employer-published annual base salary, USD. Advertised base range in Columbus, OH +2 more

Apply (opens in new tab)

You apply on the employer's own site. Six Figure Work does not handle applications.

  • LocationColumbus, OH +2 more
  • WorkplaceHybrid
  • Status at last checkSource accepting applications when checked
  • Last checked (49 min ago) · observed since
All 4 locations
  • USA, OH, Columbus
  • Irving, TX, USA - 6555 North State Highway 161 (P001)
  • USA, Remote
  • Alpharetta, GA, USA - 1110 Sanctuary (C099)

About this job

McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve – we care.

What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow’s health today, we want to hear from you.

CoverMyMeds is recognized across McKesson as a leader in AI adoption. Our Technology organization runs on an AI-First operating model, with AI embedded in how we plan, build, secure, and deliver software. We are looking for a Senior Director, AI Enablement to lead the next stage of this transformation.


This Sr Director, AI Enablement will own AI strategy, governance, and AI engineering platforms for CoverMyMeds, and will build and deliver AI products using an agentic, AI-native approach, where AI agents are designed into products and workflows from the start rather than added later. The role scales safe and measurable AI adoption across engineering and business teams, and partners with McKesson's Enterprise AI team so capabilities are built once and reused across business units. This is a builder's role for someone who combines technical depth, product delivery, strategic vision, and the ability to change how people work.


Key Responsibilities:


AI Strategy and Roadmap

  • Define and own the AI enablement strategy and multi-year roadmap for CoverMyMeds, aligned with business priorities and McKesson's enterprise AI direction.
  • Manage a portfolio of concurrent AI initiatives and a multimillion-dollar budget, prioritizing investments by business value, risk, and reuse.
  • Measure and report AI adoption, productivity, and ROI to executive leadership.

Agentic-Native Product Build and Delivery

  • Own the build and delivery of AI products and agents end to end, from discovery and design through production release and ongoing improvement.
  • Champion an agentic-native approach: design products and workflows around AI agents from the start, with humans in the loop where it matters.
  • Partner with Product and business leaders to identify high-value use cases and turn them into products that deliver measurable clinical, operational, and financial outcomes.
  • Use AI-accelerated delivery to move from idea to production in days and weeks, while holding the bar on quality, security, and compliance.

Governance and Responsible AI

  • Chair the AI Review Board and own AI usage policy, model-selection frameworks, and token allocation and cost management.
  • Ensure HIPAA, privacy, and security requirements are built into AI development and delivery processes.
  • Partner with Legal, Privacy, Security, and Compliance to enable fast, safe, and responsible AI adoption.

AI Platforms and Engineering Acceleration

  • Lead the teams that build and run reusable AI capabilities, including the AI Skills Marketplace, MCP servers, agents, and developer tooling.
  • Advance the AI-embedded SDLC, including spec-driven development, AI code review, automated vulnerability remediation, shift-left testing, and self-service developer onboarding.
  • Drive build-once, reuse-everywhere practices so shared AI assets serve multiple teams and business units.

Adoption, Enablement, and Change

  • Scale AI adoption beyond engineering to product, business, legal, finance, privacy, call center, and platform teams.
  • Own the AI training curriculum and champions network, from foundational AI literacy to advanced agentic workflows.
  • Advise senior leadership and the C-suite on AI strategy, capabilities, and risk.
  • Build a positive, curious AI culture through townhalls, ERG sessions, and hands-on enablement.

Partnership and Leadership

  • Partner with McKesson's Enterprise AI team, architecture, product, and platform leaders to align standards and avoid duplicate effort.
  • Work with external technology partners and vendors to evaluate and adopt emerging AI capabilities.
  • Hire, develop, and retain a high-performing team of engineers, architects, and enablement specialists.

Basic Qualifications:


  • Bachelor's degree in Computer Science, Engineering, Information Systems, or a related field, or equivalent experience.
  • Typically requires 13+ years of relative software engineering and technology leadership experience, including 5+ years leading engineering or platform teams.
  • 3+ years of hands-on leadership in AI or ML, including generative AI, LLMs, and agentic AI in production environments.
  • Proven track record of driving AI adoption at scale with measurable outcomes in productivity, quality, or delivery speed.
  • Demonstrated experience building and delivering AI-powered products or agents to production, with measurable business impact.
  • Experience establishing AI governance, responsible AI practices, or technology standards in a regulated environment.
  • Experience managing people, budgets, vendor relationships, and a portfolio of concurrent initiatives.

Preferred Experience:

  • Master's degree in a technical field or an MBA.
  • Healthcare, pharmacy, or health technology experience, including HIPAA and patient data protection.
  • Experience with AI developer tooling such as Claude, Claude Code, GitHub Copilot, and Model Context Protocol (MCP).
  • Experience with FHIR and healthcare interoperability standards.
  • Experience in a matrixed, multi-business-unit enterprise.

Technical Skills:

  • Generative and agentic AI: LLMs, RAG, agents, prompt and context engineering, model evaluation.
  • Agentic-native product design: multi-agent workflows, tool use, human-in-the-loop design, and agent observability and evaluation.
  • Product delivery: discovery, MVP definition, rapid iteration, and production release.
  • AI platform engineering: MCP, reusable skills and plugins, AI marketplaces, LLMOps.
  • Modern SDLC: spec-driven development, CI/CD, DevOps, Cyber Security, automated testing and code review.
  • Cloud-native architecture (GCP or AWS), APIs, and integration platforms.
  • Data foundations for AI, including data quality, tagging, and synthetic data.

Leadership:

  • Strategic vision and the ability to turn it into an executable roadmap.
  • Executive communication and influence, including explaining complex technical topics simply.
  • Change leadership: moving teams from skepticism to confident, everyday AI use.
  • Cross-functional partnership with Legal, Privacy, Security, Product, and business leaders.
  • Talent development and building inclusive, high-performing teams.
  • Data-driven decisions, with a focus on measurable outcomes and ROI.

What Success Looks Like in the First Year:

  • AI adoption continues to grow across engineering and expands further into business functions.
  • New agentic-native AI products are delivered to production with measurable business outcomes.
  • Governance keeps pace with new AI capabilities without slowing delivery.
  • Reusable AI assets are adopted across multiple teams and business units, reducing duplicate effort.
  • Clear, regular reporting on AI adoption, productivity, and ROI to executive leadership.

We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. The pay range shown below is aligned with McKesson's pay philosophy, and pay will always be compliant with any applicable regulations. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered. For more information regarding benefits at McKesson, please click here.

Our Base Pay Range for this position

$174,800 - $291,300

McKesson has become aware of online recruiting-related scams in which individuals who are not affiliated with or authorized by McKesson are using McKesson’s (or affiliated entities, like CoverMyMeds or RxCrossroads) name in fraudulent emails, job postings or social media messages. In light of these scams, please bear the following in mind:

McKesson Talent Advisors will never solicit money or credit card information in connection with a McKesson job application.


McKesson Talent Advisors do not communicate with candidates via online chatrooms or using email accounts such as Gmail or Hotmail. Note that McKesson does rely on a virtual assistant (Gia) for certain recruiting-related communications with candidates.

McKesson job postings are posted on our career site: careers.mckesson.com.

McKesson is an Equal Opportunity Employer

McKesson provides equal employment opportunities to applicants and employees, without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, age, genetic information, or any other legally protected category. For additional information on McKesson’s full Equal Employment Opportunity policies, visit our Equal Employment Opportunity page.

McKesson is committed to being an Equal Employment Opportunity Employer and offers opportunities to all job seekers including job seekers with disabilities. If you need a reasonable accommodation to assist with your job search or application for employment, please contact us by sending an email to (United States) [email protected] or (Canada) [email protected]. Resumes or CVs submitted to this email box will not be accepted.

Join us at McKesson!

Source: McKesson on Workday · View original posting (opens in new tab)

Pay in context

This role's base floor ($174,800) is above 93% of the 47 Software Engineering roles in Ohio listed on this site. Their median floor is $129,300; the middle half runs from $118,000 to $147,000.

Only jobs on this site count, and each one publishes a base salary of $100,000 or more, so this compares six-figure jobs with each other, not with the whole market. Computed Nov 8, 2026.

This range next to 6 other live McKesson roles with the nearest advertised base floor
Chart as a table
This range next to 6 other live McKesson roles with the nearest advertised base floor
RolePublished base
Senior Director, AI Enablement (this listing)$174,800 - $291,300
Senior Director - Cybersecurity Identity & Access Management$174,800 - $291,300
Principal, M&A Delivery Service Leader - Infrastructure$175,700 - $292,800
Sr. Director, Pharmacy Solutions (Oncology)$174,100 - $290,100
Senior Director Product Management$172,500 - $287,500
Principal Enterprise Architect$178,500 - $297,500
Senior Director Business Systems$181,500 - $302,500

Same $100K to $400K scale as every card. All McKesson roles · How to read the bar

Observed changes

  1. First observed on the employer's board
  2. Began meeting the published-salary criteria
Observed since
Employer-stated posting date
2026-11-06
Where this pay comes from

Location as the employer wrote it: Multiple locations (4)

$174,800 - $291,300

Method
Employer text, read with fixed rules and re-verified
Checked
Rule set
us-base-v2

The pay passage appears in the employer's own job text. Fixed, deterministic rules located it, and the passage below was checked against the stored copy of the posting.

What we verified

  • The pay figures come from the employer's own listing, quoted exactly above.
  • The pay is an annual base salary in US dollars with a minimum of at least $100,000.
  • The role was publicly listed on the employer's job board when last checked.

We do not verify what the employer will actually offer, whether the employer is still recruiting for the role, or anything beyond what the employer published. Full methodology.

Get Six Figure Work by email

Pick what you want. Nothing is selected for you unless it matches the page you are on, and nothing is sent until you confirm from a link we email you.

What would you like to receive?

A short weekly note on what employer-published pay data shows: who pays what, where, and what is changing. Once a week.

Practical notes for job seekers: interviewing, applying for six-figure roles, and making an upward move. About twice a month.

New jobs that match a search you choose. Every job listed has an employer-published base salary of $100,000 or more. At most one email a day (or weekly, your choice). Nothing is sent on days with no new matches. Alerts cover every new job, because this page has no filters.

We email you only after you confirm from a link we send to this address. We do not sell or share your address. Every email has a one-click unsubscribe link. How we handle your email.