Senior Scientist, Analytical Development and Quality Control - Early Phase
Company websitenurixtx.com (Nurix, opens in new tab)
Base salary $162K to $186K
Employer-published annual base salary, USD. Advertised base range in Brisbane, CA
You apply on the employer's own site. Six Figure Work does not handle applications.
- LocationBrisbane, CA
- WorkplaceWorkplace not stated
- Status at last checkSource accepting applications when checked
- Last checked (1 h ago) · observed since
About this job
Company
Nurix Therapeutics is a clinical stage biopharmaceutical company focused on the discovery, development, and commercialization of targeted protein degradation medicines, the next frontier in innovative drug design aimed at improving treatment options for patients with cancer and inflammatory diseases. Powered by a fully AI-integrated discovery engine capable of tackling any protein class, and coupled with unparalleled ligase expertise, Nurix’s dedicated team has built a formidable advantage in translating the science of targeted protein degradation into clinical advancements. Nurix aims to establish degrader-based treatments at the forefront of patient care, writing medicine’s next chapter with a new script to outmatch disease.
Position
Nurix Therapeutics seeks an experienced Senior Scientist to join the Analytical Development and Quality Control group. The Senior Scientist will lead analytical and QC activities in IND-enabling and early phase clinical studies. The Senior Scientist will develop analytical test methods, characterize drug substance and drug product attributes, identify and characterize technical risk, and collaborate in risk mitigation work. The Senior Scientist will oversee and execute analytical development, validation, and testing both internally and at external CDMO/CRO partners and author relevant sections of regulatory filings.
The ideal candidate must have expertise in chromatographic method development, stability studies, and phase-appropriate validation and control. The ideal candidate should have a record of contribution to first-in-human INDs and experience in vendor oversight..
This position is onsite at Nurix headquarters in Brisbane, CA.
Responsibilities:
- Characterization of drug substance and drug product attributes, identification of technical risks, and collaboration towards risk mitigation strategy
- Method development for and analytical characterization of drug substances, drug products, and product stability
- Management and/or execution of method development internally and at CDMOs/CTLs
- Management of method validation, QC testing, and reference standards at CDMOs/CTLs
- Management of forced degradation, long term stability, and predictive stability studies
- Contribution to OOS/OOE/OOT investigations
- Critical review of data, protocols, reports, specifications, and other documentation
- Trending stability data and establishing retest periods/shelf life using statistical methods
- Collaboration in the development of material control strategies and specifications
- Follow cGMP requirements and internal SOPs
Qualifications:
- Advanced degree in a relevant discipline (Chemistry, Pharmaceutics, or related field)
- Senior Scientist: BS/MS degree with 14+ years or PhD with 8+ years of industrial CMC experience
- Expertise in HPLC method development is essential
- Additional experience in techniques such as gas chromatography, NMR, mass spectrometry, particle size analysis, solid state characterization, dissolution, ICP-MS/OES, and/or FTIR
- Experience in analytical method development and validation
- Experience in management of analytical activities at CDMOs/CROs
- Solid understanding of control strategy, method validation, and retest/expiry
- Experience managing stability programs, reference standards, and retest/expiry
- Familiarity with ICH guidelines, cGMPs, and pharmacopeial chapters
- Familiarity with deviation management and change control
- Ability to critically interpret data and articulate technical concepts in multidisciplinary settings
- Ability to ensure assigned activities are completed in satisfaction of project timelines
- Strong interpersonal skills that foster collaboration within and outside of the organization
- Ability to travel domestically and internationally
Fit with Nurix Culture and Values
- Strong team orientation; highly collaborative
- Solutions and results-oriented focus
- Hands-on approach; resourceful and open to diverse points of view
Salary Range: $162K – $186K
Source: Nurix on Greenhouse · View original posting (opens in new tab)
Pay in context
This role's base floor ($162,000) is above 64% of the 318 Science & Research roles in California listed on this site. Their median floor is $143,200; the middle half runs from $120,000 to $172,100.
Only jobs on this site count, and each one publishes a base salary of $100,000 or more, so this compares six-figure jobs with each other, not with the whole market. Computed Nov 7, 2026.
This listingSenior Scientist, Analytical Development and Quality Control - Early Phase$162K to $186K
Senior Manager, Analytical Development and Quality Control - Drug Product$161,100 to $185,600
Senior Manager, electronic Quality Management System (eQMS)$158,700 to $172,100
Executive Business Partner$163,700 to $180,538
Senior Scientist, Medicinal Chemistry$147,500 to $157,500
Scientist I, Bioanalytical$141,500 to $175,600
Senior Manager / Associate Director, Regulatory Affairs CMC (Small Molecules)$187,800 to $208,600
Chart as a table
| Role | Published base |
|---|---|
| Senior Scientist, Analytical Development and Quality Control - Early Phase (this listing) | $162K - $186K |
| Senior Manager, Analytical Development and Quality Control - Drug Product | $161,100 - $185,600 |
| Senior Manager, electronic Quality Management System (eQMS) | $158,700 - $172,100 |
| Executive Business Partner | $163,700 - $180,538 |
| Senior Scientist, Medicinal Chemistry | $147,500 - $157,500 |
| Scientist I, Bioanalytical | $141,500 - $175,600 |
| Senior Manager / Associate Director, Regulatory Affairs CMC (Small Molecules) | $187,800 - $208,600 |
Observed changes
- First observed on the employer's board
- Began meeting the published-salary criteria
- Observed since
- Employer-stated posting date
- 2026-08-25
Where this pay comes from
Location as the employer wrote it: Brisbane, CA
Salary Range: $162K – $186K
- Method
- Employer text, read with fixed rules and re-verified
- Checked
- Rule set
- us-base-v2
The pay passage appears in the employer's own job text. Fixed, deterministic rules located it, and the passage below was checked against the stored copy of the posting.
What we verified
- The pay figures come from the employer's own listing, quoted exactly above.
- The pay is an annual base salary in US dollars with a minimum of at least $100,000.
- The role was publicly listed on the employer's job board when last checked.
We do not verify what the employer will actually offer, whether the employer is still recruiting for the role, or anything beyond what the employer published. Full methodology.